Circadian PM 90 capsules

Circadian PM

A multifaceted approach is needed to support falling asleep faster, staying asleep longer, and achieving higher quality, more restful sleep. Circadian PM utilizes a blend of 10 ingredients, promoting multiple mechanisms of action to nurture healthy sleep.

Mechanisms of Action

• Promotes a healthy central nervous system & promotes sleep initiation by:​
  • Increasing GABA, the primary inhibitory central nervous system neurotransmitter*​
  • Decreasing breakdown of GABA & its binding *​
  • Stimulating GABA receptor*

• ​Promotes undisrupted sleep by supporting healthy serotonin levels, leading to increased REM sleep*​
• Reduces wakefulness by supporting healthy histamine levels in the brain* ​
• Supports a healthy response to anxiety, promoting better sleep*​
• Promotes normal cytokine function to relax the central nervous system, leading to a healthy pain response*

Learn More

Complete sleep management with neurotransmitter, cytokine, and histamine support*

The importance of healthy sleep for overall health and well-being cannot be overstated. Unfortunately, achieving quality sleep is a challenge for many people. Common biological contributors to poor sleep can include physical discomfort, stress, anxiety, high histamine levels, and low levels of sleep-promoting neurotransmitters, such as gamma-aminobutyric acid (GABA).[1]

A multifaceted approach is needed to support falling asleep faster, staying asleep longer, and achieving higher quality, more restful sleep. Circadian PM utilizes a blend of 10 ingredients, promoting multiple mechanisms of action to nurture healthy sleep.

Mechanisms of Action*

• Promotes a healthy central nervous system & promotes sleep initiation by:​
  • Increasing GABA, the primary inhibitory central nervous system neurotransmitter*​
  • Decreasing breakdown of GABA & its binding *​
  • Stimulating GABA receptor*

• ​Promotes undisrupted sleep by supporting healthy serotonin levels, leading to increased REM sleep*​
• Reduces wakefulness by supporting healthy histamine levels in the brain* ​
• Supports a healthy response to anxiety, promoting better sleep*​
• Promotes normal cytokine function to relax the central nervous system, leading to a healthy pain response*

Circadian PM features PharmaGABA, the natural form of GABA, made through a natural fermentation process. This results in a superior form of GABA vs other synthetic options. Synthetic forms of GABA are less bio-available, as their molecular size is too large to pass the blood-brain barrier. PharmaGABA is easily absorbed and binds to GABA receptors in the peripheral nervous system, activating the parasympathetic nervous system. This activation of the parasympathetic nervous system by PharmaGABA is measurable within 5 to 30 minutes after ingestion .*

The unique blend of herbs, nutrients, and amino acids make Circadian PM a must-have formulation for patients dealing with sleep challenges and those who want to improve the quality of their sleep utilizing natural methods.

[1] The contributing factors to poor sleep experiences in according to the university students: A cross-sectional study Altun I et al. J Res Med Sci. 2012 Jun; 17(6): 557-561.

Supplement Facts / Dosing

Ingredients

• CalmNight Blend | 2148mg
  • Glycine, Valerian Extract (Valeriana officinalis) (root), CurcuWIN Turmeric Extract, Lemon Balm Extract (Melissa officinalis) (leaf), Magnolia Extract (Magnolia officinalis) (bark), 5 HTP (5-hydroxytryptophan), L-theanine, PharmaGABA (Gamma-aminobutyric acid)
• HistaCalm | 126mg
  • Black Cumin Extract (Nigella sativa) (seed), Stinging Nettle Extract (leaf)

Other Ingredients: Vegetarian cellulose (capsule shell)

Vegan

Manufactured without eggs, fish, crustacean shellfish, tree nuts, peanuts, wheat, corn and gluten. Produced in a facility that may process other ingredients containing these allergens.

Suggested Use: As a dietary supplement, take 3 capsules once daily before bed, or as directed by your healthcare professional.

Caution: Do not use while pregnant or nursing.