Brand: Designs For Health

Homocysteine Supreme 60 capsules

In Stock

Clinic Approval Needed

Adding to cart… The item has been added

Product Description

Homocysteine Supreme™

About Homocysteine Supreme

Homocysteine Supreme is a formula that contains synergistic nutrients, such as 5-methyltetrahydrofolate and folate in the bioactive, bioidentical form. The compounds in the product are widely recognized to facilitate efficient homocysteine metabolism while ensuring an optimally functioning homocysteine pathway with the production of neurotransmitters (dopamine and norepinephrine) and sulfur-containing amino acids (cysteine and taurine). All that combined help provide the human body with the means necessary for optimal functioning. Among the systems benefited from the ingredients of the formula are the cardiovascular, the brain, the immune, and the skeletal (cartilage and joint structure, in particular) while also promoting detoxification.

How Homocysteine Supreme Works

Homocysteine is a natural amino acid that comes from the metabolism of methionine (an essential amino acid). Produced by the body itself, homocysteine is involved in a cycle where methionine metabolizes to homocysteine, and the latter recycles back to the first, and so on. The reason for this is that this process helps synthesize the nutrients necessary for various biochemical reactions, such as cardiovascular and brain health, optimal bone and cartilage structure, healthy immune function, and detoxification.

For all this to succeed, it is paramount the pathway between homocysteine and methionine is healthy functioning and provided with the nutrients required (i.e., vitamin B) to synthesize the needed enzymes. This is where Homocysteine Supreme comes to play, ensuring there are no roadblocks during the procedure mentioned above that could lead to an unwanted increase of homocysteine levels.

Homocysteine Supreme also includes vitamins B12 and B6 for proper metabolism of homocysteine, alongside N-acetyl L-cysteine and trimethylglycine compounds, which play a vital role in biological and biochemical functions, including the synthesis of a key antioxidant, namely glutathione.

Importance of Homocysteine in the Human Body

It is paramount to keep homocysteine at optimal levels within the bloodstream as a means to ensure good health overall. Failing to maintain these levels within a normal range can lead to blood clots in the blood vessels and arterial damage. Other common conditions associated with high homocysteine are:

  • Heart attack Stroke
  • Atherosclerosis (when fats and other substances build up in the walls of the arteries)
  • Bone thinning (aka osteoporosis)
  • Dementia
  • Alzheimer’s disease
  • Coronary artery disease

Symptoms of Increased Homocysteine

Most of the time, increased homocysteine levels indicate a deficiency in either folate or vitamin B12. Unfortunately, there are usually no symptoms that could telltale a boost in homocysteine levels in adults. Things are clearer with children, though, who exhibit some symptomatology. Nevertheless, these (the symptoms) are mainly connected to a vitamin deficiency and vary among one another.

For instance, those with vitamin B12 deficiency have pale skin, fatigue, mood swings, mouth sores, dizziness, a tingling sensation in the feet, legs, arms, or hands (like needles or pins), and weakness. People with folate deficiency, on the other hand, demonstrate more subtle symptoms, which usually involve growth issues, tongue swelling, mouth sores, and fatigue. Now, there are also cases of individuals suffering from anemia, who have additional symptoms, such as irregular heartbeat, forgetfulness, mental confusion, unsteady movements, muscle weakness, and weight loss.

Causes of Elevated Homocysteine Levels

Besides vitamin B or folate deficiency, factors that may also contribute to high homocysteine levels are:

  • Genetics
  • Specific medications
  • Kidney disease
  • Psoriasis
  • Low thyroid hormone levels
  • Poor diet
  • Stress
  • Poor nutrient absorption

The depletion of B vitamins obstructs the process of altering homocysteine into methionine and back. Any excess homocysteine in the bloodstream can cause the arterial walls to become inelastic and narrow due to damage to the lining of these walls. Lead, mercury, and other heavy metals may also interfere with this process as well, as they both deplete Vitamin B12, which is necessary for this conversion.

Homocysteine Supreme Ingredients

Rivoflavin (Vitamin B2)

Vitamin B6 (as Pyridoxine Hydrochloride)

Folate Vitamin B12 (as Methylcobalamin)







Other ingredients: Vegetable stearate, silicon dioxide, microcrystalline cellulose.


  • The formula uses non-GMO ingredients
  • The recommended dosage is two (2) capsules every day with meals unless otherwise instructed by your healthcare practitioner.
  • Always consult your doctor before taking any dietary or nutritional supplements, especially if you are taking medications or are pregnant/nursing.

About the Manufacturer

Designs for Health is a family-owned manufacturer of top-quality natural supplements to help promote optimal health and contribute to successful patient outcomes. Established in 1989, they have become a leading innovator in the nutritional supplements industry and one of the fastest-growing brands in the healthcare practitioner channel. Their products are sold exclusively to health professionals and are developed in science-based natural medicine.

Among their best selling products are Complete Mineral Complex, Inflammatone, Tricobalamin Lozenges, and NeuroMag.