Brand: Life Extension

Pro-Resolving Mediators 30 soft gels

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MSRP: $28.00
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Product Description

Pro-Resolving Mediators

Helps maintain a healthy post-inflammatory response for whole-body health

This formula uses SPM precursors from marine oil to promote the natural clearing of cellular debris, help maintain a healthy balance of cytokine compounds, and support healthy tissue rejuvenation.

Product Details

A healthy dietary regimen should include nutrients that promote a healthy inflammatory response, as well as those that help maintain a healthy post-inflammatory response. Pro-Resolving Mediators do just that: promote a healthy post-inflammatory response, which in turn supports whole-body health.

Derived from Marine Oil

Resolvins and maresins are the two principle types of specialized pro-resolving mediators, or SPMs. They're created by the body from fatty acids such as EPA and DHA omega-3s.

Why not just take a fish oil supplement? Because fish oil is not completely converted to SPMs, and may not obtain sufficient SPM levels. Fish oil and SPMs also perform distinct activities in the body and are not interchangeable. Research indicates that ingesting SPMs and precursors like 17-HDHA and 18-HEPE is better than taking fish oil when a healthy post-inflammatory response is required, in order to promote whole-body health.


The body's natural biological response to inflammation can cause cellular debris. This debris can affect the function of otherwise-healthy cells. SPMs encourage the body's existing pathways for naturally identifying and removing cellular debris, as well as recycling cells that no longer function optimally.


The body naturally maintains a balance between chemical compounds called cytokines. With normal aging, this natural balance declines. SPMs help maintain a healthy balance of cytokines in the body.


It is important to support the natural biological process for rejuvenating youthful, healthy system-wide functionality. SPMs do just that by promoting the body's natural processes for revitalizing healthy skin, organs and other vital tissues.

Part of a Healthy Whole-Body Regimen

Pro-resolving mediators helps maintain the body's healthy post-inflammatory response. We recommend taking SPMs along with Curcumin Elite Turmeric Extract as part of a comprehensive health regimen.


Not for sale outside the USA.

Supplement Facts

Serving Size 1 softgels
Amount Per Serving
Total Fat0.5 g
  • 5 mg
    Marine Lipid Concentrate500 mg
    [providing 300 mcg of Pro-Resolving Mediators including 18-hydroxyeicosapentaenoic acid (18-HEPE), 17-hydroxydocosahexaenoic acid (17-HDHA), & 14-hydroxydocosahexaenoic acid (14-HDHA)]
    Other ingredients: highly refined marine oil concentrate, (squid, anchovy, sardine, herring, mackerel), gelatin, olive oil, glycerin, purified water, lemon flavor, mixed tocopherols.


    Dosage and Use

    • Take one (1) softgel daily, with or without food, or as recommended by a healthcare practitioner.
    • Store tightly closed in a cool, dry place.


    • Do not purchase if outer seal is broken or damaged.
    • When using nutritional supplements, please consult with your physician if you are undergoing treatment for a medical condition or if you are pregnant or lactating.

    To report a serious adverse event or obtain product information, contact 1-866-280-2852.