FEM+ 60 capsules 500 milligrams

FEM+

SKU: PAN37

Fem +

60 x 500mg Capsules

Actions

• Regulates menopausal and peri-menopausal symptoms.
• Reduces flushing and agitation.
• Aids with sleep.
• Anti-aging properties particularity skin and muscle tone.
• Aids with 'Adrenal Exhaustion.

† Daily Value not established.

Other Ingredients: Vegetable cellulose (hypromellose); Vegetable Stearic Acid; Microcrystalline Cellulose and Vegetable Magnesium Stearate.

Key Ingredients

Cimicifuga w/ 18% standardized Triterpene Glycoside

Triterpene Glycoside: One of the first studies involved 36 postmenopausal women treated with Remifemin (an alcoholic extract of black cohosh roots containing Triterpene Glycoside). Treatment for 12 weeks resulted in a decrease in menopausal symptoms, with no reported side effects. These results were supported by a similar study published the next year. This 12-week study of 50 postmenopausal women assessed symptoms utilizing the Profile of Mood States (POMS) and Clinical Global Impression Scale (CGI). Triterpene Glycoside treatment resulted in a significant improvement in both the POMS and CGI scales. The only side effect noted was mild gastrointestinal disturbances in four patients.

References

Combest, W. L., & Winchester, V. A. (1999). Black Cohosh. US PHARMACIST, 24, 46-55.

Mahady, G. B. (2005). Black Cohosh (Actaea/Cimicifuga racemosa). Treatments in endocrinology, 4(3), 177-184.

Angelica Sinensis (Dang Gui)

Estrogenic activity of standardized extract of Angelica sinensis.

In this study the estrogenic activity of a commercial standardized extract of the roots of Angelica sinensis, used to relieve climacteric symptoms was evaluated using in vivo tests such as the degree of cornification of vaginal epithelium, uterotrophic assays and serum LH concentration in ovariectomized rats.

Furthermore, the effects on the estrous cycle in rat's were investigated. The results obtained have shown that the administration of a standardized ethanol extract in ovariectomized rats exhibited a stimulation of the uterine histoarchitecture, a significant cornification in the vaginal epithelium and a reduction of serum LH concentration showing the estrogenic nature of the extract. Furthermore, the administration of the extract in intact female rats provoked a significant modification of the vaginal smear in 67% of treated rats. The estrous cycle thus modified was characterized by a prolonged estrus stage with a temporary reduction of the regular cyclicity.

Reference

Circosta C, Pasquale RD, Palumbo DR, Samperi S, Occhiuto F. Phytother Res. 2006 Aug;20(8):665-9.

Panax ginseng (Ren Shen)

Study on the Changes of Rat Testis Androgen Receptor mRNA Expression and Plasma Testosterone after Cold Stress

Objective To study the effect of ginseng polysugar on the mRNA expression of testis tissue androgen receptor and plasma testosterone change after cold stress. Methods Rats were divided into control group, cold stres sex periment group and cold stress ginseng polysugar group, testis tissue androgen receptor mRNA expression was determined by rat androgen receptor cDNA probe dot blotting. Testosterone was determined by radio immunoassay kit (RIA kit). Results The content of testosterone (nmol/ L) was 10.93 ± 1.44 in control group, 6.06 ± 1.78 in cold stress experiment group, 8. 01 ± 1.38 in cold stress ginseng polysugar group. There was a significant synthesis difference between cold stress group and control group(P0.05). Dot-blot: the mRNA expression of androgen recepter in cold stress group was weaker than that in control group, cold stress ginseng polysugar group was more than that in cold stress group. Conclusion Testosterone has identical change with androgen receptor mRNA expression,ginseng polysugar has upregulation action for androgen receptor mRNA expression, and promote testosterone.

Reference

WANG Hong-jun, FENG Li, CHU Zheng, YU Ning, YANG Qing, ZHANG zhi-qiang, WANG Li-qiang, WU Yi-min. Shi Zhen Guo Yi Guo Yao. 2008; 19(4): 929-930.

Rehmannia glutinosa (Shu Di)

Radix Rehmanniae Preparata, Radix Paeoniae Alba and Radix Angelicae sinensis have phytoestrogenic effects. But thed ata werent consistent with in vitro and in vivo assay of Rhizoma Chuan xiong.

Reference

Hao Q, Wang J, Niu J, Zhao P, Cui Y, Sun L, Xue X. Zhongguo Zhong Yao Za Zhi. 2009 Mar;34(5):620-4.

Epimedium sagittatum (Yin Yang Huo)

Experimental studies on anti-Partial androgen deficiency effects of icariin

Objective To explore the protective effects of lcariin on partial androgen deficiency rat. Methods Reproduction system of 15 months male rat was first damaged by CYP. After ig. Icariin and ip. Propyltestosterone, the content of serum T, LH, FSH, BGP and StrACP were determined. The change of histology of the testis and the penis were observed by microscope with the method of H-E staining and TUNEL method respectively. Results (1) As to the contents of serum T, T group 04, 96±11.42)ng/ml and ICA group (10.94±2.04)ng/ml were statistically higher than C group 0.01±0.41)ng/ml and M group (0.79±0.45)ng/m1. Furthermore, Tgroup as higher than ICA group, and C group as higher than Mgroup (P0, 05); (2) Serum BGP, T group (4.50±1, 70)ng/ml and ICA group (3.44±0.51) ng/ml were statistically higher than C group (1. 82±0.50)ng/ml and M group (1.22±0.50) ng/ml (P0.05); (3) Serum Str ACP, T group (25.73±7.57)U/L and ICA group (19.99±8.63)U/L were statistically lower than C group (51.32±14.16)U/L and M group (64.89±12.57)U/L, Furthermore, C group was lower than M group (P0, 05); (4) As to the cell apoptosis rate in rat penis, T group (22.65±5.17)% and ICA group (34.26±3.45)% were statistically lower than M group (48.28±6.74)%, (P0.05). Conclusion lcariin possesses the anti-partial androgen deficiency effects, and is beneficial to PADAM..

Reference

Zhang Zhenbao, Yang Qingtao. Zhong Guo Nan Ke Xue Za Zhi. 2006; 20(3): 47-50.

Suggested Use: 2 - 4 capsules 2 times daily

Combinations

• For Vaginal dryness add Mongolian Seabuckthorn Oil
• Daniel Weber's recommendation is to start with FEM+, slowly increasing dosage to the most severe stage and then introducing CHANGE at a low dose. At this point FEM+ begins to be reduced and CHANGE increases in dosage. Throughout the menopause include EVO Fusion in the protocol.

Warning: Avoid with oestrogen sensitive tumours.

Caution: Only for peri-menopausal and menopausal women.

Does not contain: Wheat, gluten, soy, milk, eggs, fish, crustacean shellfish, tree nuts, peanuts