Designs For Health
Pure Encapsulations Nrf2 Detox
What Nrf2 Detox is Best For
Nrf2 Detox may be used for the following:
- Antioxidant support
- Detoxification support
How Nrf2 Detox Works
Cruciferous vegetables of the brassica family have long been recognized for their ability to support detoxification thereby maintaining healthy cells and tissues. Cruciferous vegetables, like broccoli, cauliflower, Brussels sprouts and kale, are the richest sources of glucosinolates, which are considered to be the most bioactive constituents. Glucosinolates are converted in the body to isothiocyanates after they are ingested and hydrolyzed. The isothiocyanate sulforaphane is one of the most powerful activators of phase II enzyme function in the liver, supporting toxin elimination. Sulforaphane and resveratrol promote the activity of nuclear factor erythroid 2-related factor 2 (Nrf2), a transcription factor that supports robust, long-lasting expression of numerous genes responsible for detoxification and protection against oxidative stress. Among these genes are glutathione peroxidase, superoxide dismutase and various phase II enzymes, such as glutathione sulfotransferases. Nrf2 also supports expression of glutathione glutamylcysteinyl ligase, which is responsible for a critical step in the biosynthesis of glutathione, a vital component of cellular antioxidant and detoxification systems. Found in virtually every cell of the body, glutathione plays essential roles in protein synthesis, synthesis and repair of DNA, enzyme function, transport, and cell maturation. Optimal levels of glutathione have been associated with physical and mental health. The highest concentration of glutathione is found in the liver, where it offers antioxidant support, protects tissue and maintains detoxification. In a randomized clinical trial, supplementation with 250 and 1,000 mg of Setria glutathione per day increased glutathione levels in the blood after one, three and six months. At six months, mean glutathione levels in the high-dose group increased 30-35% in erythrocytes, plasma and lymphocytes, and 260% in buccal cells (P0.05). In the low-dose group, mean glutathione levels increased 17% and 29% in blood and erythrocytes, respectively (P0.05). Both glutathione dose groups showed support for antioxidant defenses, indicated by decreases in the oxidized-to-reduced-glutathione ratio in whole blood after six months.*
Three-ingredient combination designed to support detoxification and antioxidant defenses.*
Nrf2 Detox Serving Size
1 capsule, 1-3 times daily, with meals.
Nrf2 Detox Ingredients
|Amount Per Serving - Each vegetarian capsule contains:|
|Broccoli (Brassica oleracea italica) sprout concentrate (whole plant) (standardized to contain 1,000 mcg sulforaphane)||250 mg|
|Setria glutathione (reduced form)||250 mg|
|resVida resveratrol (as trans-resveratrol)||15 mg|
other ingredients: vegetarian capsule (cellulose, water)
Nrf2 Detox Side Effects
Consult your healthcare provider.
Nrf2 Detox Where to Buy
Nrf2 Detox product is available only from licensed healthcare professionals. Buy Nrf2 Detox Online here at AcuAtlanta.net or our clinic.