Brand: Microbiome Labs

MegaSporeBiotic 60 capsules

In Stock

MSRP: $63.99
Was: $63.99
Now: $53.50
( You save $10.49 )
Adding to cart… The item has been added

Product Description

About Megasporebiotic

Megasporebiotic by Microbiome Labs is a 100% spore-based probiotic with potent antioxidant properties that have been clinically shown to maintain the healthy function of the gut barrier. The broad-spectrum probiotic formula is actually the first of its kind that has been evidenced to improve leaky gut by 60% in 30 days.

It contains a blend of 5 Bacillus spores which are found to boost gastrointestinal immunity. Their bi-phase life cycle* enables them to remain in sleep mode when in a harsh environment and reactivate themselves when they enter the human digestive tract or another favorable environment. Then, they start colonizing in the gut. The product comes with a 5-year shelf-life and can preserve the efficacy of its ingredients without requiring refrigeration.

*This refers to Bacillus spores’ inherent survivability that allows them to shift from a dormant form into their active form (and vice versa) depending on the environment. That is how they manage to survive digestion without needing refrigeration or enteric-coated capsules. When in their dormant form, they surround themselves with a tough outer layer called endospore that protects them from environmental factors such as lack of oxygen, acid, pressure, heat, and light.

How Megasporebiotic Works

Due to its unique formula, Megasporebiotic effectively reconditions the gut. In doing so, it encourages the growth of health-promoting gut bacteria while also improving microbial variety in the gastrointestinal.

The problems start when chronic inflammatory conditions are left untreated or go undiagnosed. Most of the time, the intestinal tissues get damaged, which leads back to inflammation and then tissue damage and so on - a cycle that never ends. The first step towards helping those damaged intestinal tissues heal is to recondition the intestinal tract. That is when Megasporebiotic comes in and effectively gets the job done the way described earlier.

The Three Aspects of Gut Health

To function properly and enjoy a healthy function, the gut microbiome relies heavily upon three fundamental factors:

  • The physical structures
  • The microbial population
  • The regulatory immune system

If one of the three is malfunctioning, the gastrointestinal gut health is adversely affected as well. For that reason, it is critical to follow therapies that address all three aspects of gut health and provide a complete restoration of its normal function. Microbiome Labs’ Total Gut Restoration system has been specifically designed to provide healthcare practitioners with the tools they need to combat chronic diseases effectively.

This system comprises of:

The first factor affecting GI tract health (gut reconditioning) is addressed appropriately with Megasporebiotic, as described above. Once this is achieved, the next step is to promote a diverse and strong microbiome by reinforcing the changes that have occurred. Increasing the growth of primary strains, such as Bifidobacteria or Faecalibacterium prausnitzii is key in this case. That is what MegaPreBiotic does, the first Precision Prebiotic supplement that comprises of oligosaccharides (non-digestible and clinically-tested) which feed beneficial bacteria and improve microbial diversity.

The final step is to ensure the intestinal lining remains healthy and protected. Rebuilding the mucosal layer is a prerequisite here, which will also help heal the intestinal barrier function. The same brand has formulated MegaMucosa for that purpose, which comes packed with key amino acids, dairy-free immunoglobulins, and a specific flavobiotic that combats leaky gut (aka barrier dysfunction).

What is Leaky Gut Syndrome?

This digestive condition affecting the lining of the intestines or increased by intestinal permeability. This happens when large holes or cracks in the intestinal lining allows partially digested foods, toxins, and bugs to penetrate the tissues beneath it. Inflammation and changes in gut flora can lead to digestive issues and extend to the rest of the body - possibly playing a part in several chronic diseases.


The formula contains a total of five Bacillus spores:

Bacillus Licheniformis – It produces a wide range of B vitamins, as well as proteases (enzymes that break down peptides and proteins) for the proper digestion of proteins.

Bacillus Indicus HU36 – It produces vitamins, quinols, and RDA carotenoids levels (lutein, B-carotene, astaxanthin, lycopene).

Bacillus Subtilis HU58 – It fosters the healthy development of an enzyme called GALT (it helps break down sugar) while also producing vitamin K2 and nattokinase (an enzyme that boosts reactions in the human body).

Bacillus Clausii – An immune function-supporting Bacillus spore that also helps sustain efficacy during antibiotic treatment.

Bacillus Coagulans – It protects the immune system function and produces a specific form of lactic acid (L+ optical).

Serving Size

The recommended serving size is one capsule (or ½ capsule if one capsule is too strong) with food. The goal is to increase to 2 capsules a day gradually. To get there, start with taking 1 capsule (or less) every other day for one week. Then, switch to one capsule every day for another week. On the third week, you will be able to take 2 capsules daily.


  • In some cases, you may need to start with ¼ capsule and slowly work your way to 2 capsules per day.
  • If you experience changes in the bowel movements, loose stools, and/or abdominal cramping, do not worry. It means that the formula is doing its job. The symptoms will go away in a couple of days.
  • Sensitive individuals or children may require a smaller dosage.


  • Soy-free
  • Allergen-free
  • GMO-free
  • Dairy-free
  • Gluten free
  • Non-GMO
  • The only product that includes HU36TM or Bacillus Indicus - a spore that produces lycopene, astaxanthin, zeaxanthin, beta-carotene and lutein - carotenoids in the GI tract.
  • 100% survivability in the GI tract
  • No refridgeration necessary

About Microbiome Labs

Microbiome Labs is a supplement manufacturing company founded by microbiologists Kiran Krishnan and Dr. Tom Bayne. The two professionals combined their clinical expertise and probiotic research and formulated the first gut health-promoting supplement after discovering Bacillus spores, which is considered the next big probiotic in the supplement industry. Their mission is to make vibrant health accessible to everybody. So far, they have helped more than 334,000 people change their lives.